Protein Name:
Histone deacetylase 5
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UniprotKB/SwissProt ID: Q8RX28 (Q8RX28)
Gene Name:
HDA5
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (Probable). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (Probable). Histone deacetylases act via the formation of large multiprotein complexes (PubMed:25922987). Involved in the regulation of flowering time by repressing FLC and AGL27/MAF1 expression (PubMed:25922987). Forms a histone deacetylase complex with HDA6, FLD and MSI4/FVE that represses FLC gene expression to control flowering time (PubMed:25922987). Unlike its tandem duplication HDA18, HDA5 does not seem to be required for the cellular patterning in the root epidermis (PubMed:16176989)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8RX28
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
49 |
DTPDGEDHPE C PDRIRVIWEK |
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