Protein Name:
Hydroxyacid-oxoacid transhydrogenase, mitochondrial
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UniprotKB/SwissProt ID: Q8R0N6 (Q8R0N6)
Gene Name:
Adhfe1
Organism: Mus musculus (Mouse)
Function: Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2-hydroxyglutarate (D-2-HG). L-3-hydroxybutyrate (L-3-OHB) is also a substrate for HOT when using 2-KG as hydrogen acceptor, resulting in the formation of D-2-HG (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8R0N6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
260 |
TAIPYSMRSP C PSNPIQRPAY |
CHHHHHHHHH H HHHHHHHCCC |
6.43% |
21278135
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