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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Large ribosomal subunit protein mL62

UniprotKB/SwissProt ID: Q8R035 (Q8R035)

Gene Name: Mrpl58

Organism: Mus musculus (Mouse)

Function: Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit (PubMed:20869366). Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR052104 Mito_Release_Factor_mL62
IPR000352 Pep_chain_release_fac_I

The S-nitrosylation sites of Q8R035

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 82 IPLDRLSISY C RSSGPGGQNV  CCCHHHHCCC C CCCCEEEECC  2.44% 21278135