Protein Name:
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
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UniprotKB/SwissProt ID: Q8R010 (Q8R010)
Gene Name:
Aimp2
Organism: Mus musculus (Mouse)
Function: Required for assembly and stability of the aminoacyl-tRNA synthase complex (PubMed:12060739). Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation (PubMed:12819782). Blocks MDM2-mediated ubiquitination and degradation of p53/TP53 (PubMed:18695251). Functions as a proapoptotic factor (PubMed:16135753)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8R010
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
306 |
PTNVQRWLKS C ENLAPFSTAL |
CCCCCCCCCC C CCCCEEEECC |
3.72% |
21278135
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