Protein Name:
EKC/KEOPS complex subunit Tprkb
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UniprotKB/SwissProt ID: Q8QZZ7 (Q8QZZ7)
Gene Name:
Tprkb
Organism: Mus musculus (Mouse)
Function: Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8QZZ7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
167 |
RIGTLLDAII C RMSTKDVL-- |
CCHHHHHHCC H HHHHHHHHHC |
2.14% |
21278135
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