Protein Name:
Acetyl-CoA acetyltransferase, mitochondrial
|
UniprotKB/SwissProt ID: Q8QZT1 (Q8QZT1)
Gene Name:
Acat1
Organism: Mus musculus (Mouse)
Function: This is one of the enzymes that catalyzes the last step of the mitochondrial beta-oxidation pathway, an aerobic process breaking down fatty acids into acetyl-CoA. Using free coenzyme A/CoA, catalyzes the thiolytic cleavage of medium- to long-chain 3-oxoacyl-CoAs into acetyl-CoA and a fatty acyl-CoA shortened by two carbon atoms. The activity of the enzyme is reversible and it can also catalyze the condensation of two acetyl-CoA molecules into acetoacetyl-CoA. Thereby, it plays a major role in ketone body metabolism
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of Q8QZT1
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
116 |
LGAGLPISTP C TTVNKVCASG |
CHHHHHHHHH H HHHHHHHHHH |
5.16% |
24895380
22588120
21278135
|
| 2 |
139 |
AIMMASQSLM C GHQDVMVAGG |
CHHHHHHHHH H HHHHHHHHHH |
5.51% |
22178444
21278135
|
| 3 |
193 |
DVYNKIHMGN C AENTAKKMNI |
CHHHHHHHHH H HHHHHHHHHH |
4.1% |
22178444
21278135
23748021
|
| 4 |
410 |
KPGEFGLASI C NGGGGASALL |
CHHHHHHHHH H HHHHHHHHHH |
3.42% |
21278135
|
|
