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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: SHC SH2 domain-binding protein 1

UniprotKB/SwissProt ID: Q8NEM2 (Q8NEM2)

Gene Name: SHCBP1

Organism: Homo sapiens (Human)

Function: May play a role in signaling pathways governing cellular proliferation, cell growth and differentiation. May be a component of a novel signaling pathway downstream of Shc. Acts as a positive regulator of FGF signaling in neural progenitor cells

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Midbody. Cytoplasm, cytoskeleton, spindle

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039448 Beta_helix
IPR006626 PbH1
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
IPR045140 SHCBP1-like

The S-nitrosylation sites of Q8NEM2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 271 FLNLRSSLSN C NSDSEQENIS   
2 46 LFQDEDSCSD C SYRDKPGSSL   
3 464 KTTLENCVLQ C ETTGVTVRTS   
4 591 ERVDLEELIE C ATGKMELCAR   
5 612 TDPSEQVEGN C EIVNELIAAS   
6 93 RAYQDYILAD C KASEVQEFTA