Protein Name:
Trinucleotide repeat-containing gene 6A protein
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UniprotKB/SwissProt ID: Q8NDV7 (Q8NDV7)
Gene Name:
TNRC6A
Organism: Homo sapiens (Human)
Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent repression of translation and for siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As a scaffolding protein, associates with argonaute proteins bound to partially complementary mRNAs, and can simultaneously recruit CCR4-NOT and PAN deadenylase complexes
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, P-body
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8NDV7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
225 |
VSSTSDSSTN C KNAVVSDLSE |
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| 2 |
800 |
LRWGDSKGSN C QGGWEDDSAA |
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| 3 |
822 |
GMVKSNQWGN C KEEKAAWNDS |
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