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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Polypeptide N-acetylgalactosaminyltransferase 6

UniprotKB/SwissProt ID: Q8NCL4 (Q8NCL4)

Gene Name: GALNT6

Organism: Homo sapiens (Human)

Function: Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor (PubMed:10464263, PubMed:31932717). May participate in synthesis of oncofetal fibronectin (PubMed:10464263). Has activity toward MUC1A, MUC2, EA2 and fibronectin peptides (PubMed:10464263). Glycosylates FGF23 (PubMed:31932717)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Golgi apparatus membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045885 GalNAc-T
IPR001173 Glyco_trans_2-like
IPR029044 Nucleotide-diphossugar_trans
IPR035992 Ricin_B-like_lectins
IPR000772 Ricin_B_lectin

The S-nitrosylation sites of Q8NCL4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 597 QLIRNSGSGT C LTSQDKKPAM