Protein Name:
Equilibrative nucleobase transporter 1
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UniprotKB/SwissProt ID: Q8NBI5 (Q8NBI5)
Gene Name:
SLC43A3
Organism: Homo sapiens (Human)
Function: Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobases such as adenine, guanine and hypoxanthine (PubMed:26455426, PubMed:32339528). May regulate fatty acid (FA) transport in adipocytes, acting as a positive regulator of FA efflux and as a negative regulator of FA uptake (By similarity) Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793). Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793) Sodium-independent purine-selective nucleobase transporter which mediates the equilibrative transport of extracellular purine nucleobase adenine (PubMed:30910793). Mediates the influx and efflux of the purine nucleobase analog drug 6-mercaptopurine across the membrane (PubMed:30910793)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Basolateral cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8NBI5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
226 |
PLPPNYSYGL C PGNGTTKEEK |
CCCCCCCHHH H HHHHHHHHHH |
3.35% |
22178444
18335467
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