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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glutamine amidotransferase-like class 1 domain-containing protein 1

UniprotKB/SwissProt ID: Q8NB37 (Q8NB37)

Gene Name: GATD1

Organism: Homo sapiens (Human)

Function: Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary) (PubMed:37267905, PubMed:37267906). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (PubMed:37267905)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted. Early endosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029062 Class_I_gatase-like
IPR050325 Prot/Nucl_acid_deglycase

The S-nitrosylation sites of Q8NB37

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 179 VEDFVKDSGA C FSASEPDAVH   
2 94 ARYHALLIPS C PGALTDLASS