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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Putative E3 ubiquitin-protein ligase UBR7

UniprotKB/SwissProt ID: Q8N806 (Q8N806)

Gene Name: UBR7

Organism: Homo sapiens (Human)

Function: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR040204 UBR7
IPR047506 UBR7-like_UBR-box
IPR011011 Znf_FYVE_PHD
IPR013083 Znf_RING/FYVE/PHD
IPR003126 Znf_UBR

The S-nitrosylation sites of Q8N806

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 260 EVKVEQNSEP C AGSSSESDLQ   
2 374 MNRVQQVELI C EYNDLKTELK   
3 46 AVLGGSDSEK C SYSQGSVKRQ