Protein Name:
Type 2 DNA topoisomerase 6 subunit B-like
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UniprotKB/SwissProt ID: Q8N6T0 (Q8N6T0)
Gene Name:
TOP6BL
Organism: Homo sapiens (Human)
Function: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with SPO11, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Chromosome
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR028040
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TopoVIB-like |
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The S-nitrosylation sites of Q8N6T0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
57 |
DEKPRTLMTD C LVIKHFLRKI |
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