Protein Name:
Actin filament-associated protein 1
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UniprotKB/SwissProt ID: Q8N556 (Q8N556)
Gene Name:
AFAP1
Organism: Homo sapiens (Human)
Function: Can cross-link actin filaments into both network and bundle structures (By similarity). May modulate changes in actin filament integrity and induce lamellipodia formation. May function as an adapter molecule that links other proteins, such as SRC and PKC to the actin cytoskeleton. Seems to play a role in the development and progression of prostate adenocarcinoma by regulating cell-matrix adhesions and migration in the cancer cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton, stress fiber
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8N556
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
395 |
THIVSIPLRG C EVIPGLDSKH |
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| 2 |
471 |
SVIQTAKQTF C FMNRRVISAN |
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| 3 |
684 |
RTLENSPISS C DTSDTEGPVP |
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