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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Mesoderm induction early response protein 1

UniprotKB/SwissProt ID: Q8N108 (Q8N108)

Gene Name: MIER1

Organism: Homo sapiens (Human)

Function: Transcriptional repressor regulating the expression of a number of genes including SP1 target genes. Probably functions through recruitment of HDAC1 a histone deacetylase involved in chromatin silencing

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus. Nucleus. Cytoplasm. Cytoplasm. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000949 ELM2_dom
IPR009057 Homeodomain-like_sf
IPR040138 MIER/MTA
IPR045787 MIER1/3_C
IPR001005 SANT/Myb
IPR017884 SANT_dom

The S-nitrosylation sites of Q8N108

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 109 EDADNDDNSG C SGENKEENIK   
2 293 EELSVWTEEE C RNFEQGLKAY