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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Calcineurin B-like protein 2

UniprotKB/SwissProt ID: Q8LAS7 (Q8LAS7)

Gene Name: CBL2

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Acts as a calcium sensor. CBL proteins interact with CIPK serine-threonine protein kinases. Binding of a CBL protein to the regulatory NAF domain of a CIPK protein lead to the activation of the kinase in a calcium-dependent manner. Binds four calcium ions per subunit. Mediates the activation of AKT1 by CIPK proteins (CIPK6, CIPK16, and CIPK23) in response to low potassium conditions and in the context of stomatal movement. Mediates the inactivation of the proton pump AHA2 by CIPK11. Probably involved in regulating signaling responses to abscisic acid

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Vacuole membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045198 CNBL1-10
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom