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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Homoserine kinase

UniprotKB/SwissProt ID: Q8L7R2 (Q8L7R2)

Gene Name: HSK

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate (PubMed:15703056). Is specific for L-homoserine and cannot use other substrates such D-serine, L-serine, D-threonine and L-threonine, galactose or D-homoserine in vitro. Required for susceptibility to the downy mildew pathogen Hyaloperonospora parasitica

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Plastid, chloroplast stroma

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013750 GHMP_kinase_C_dom
IPR036554 GHMP_kinase_C_sf
IPR006204 GHMP_kinase_N_dom
IPR006203 GHMP_knse_ATP-bd_CS
IPR000870 Homoserine_kinase
IPR020568 Ribosomal_Su5_D2-typ_SF
IPR014721 Ribsml_uS5_D2-typ_fold_subgr

The S-nitrosylation sites of Q8L7R2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 116 TKLSTNPLRN C AGIAAIATMK