UniprotKB/SwissProt ID: Q8K4Q8 (Q8K4Q8)
Gene Name:
Colec12
Organism: Mus musculus (Mouse)
Function: Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Also binds to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells (By similarity). Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane
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