Protein Name:
sn-1-specific diacylglycerol lipase ABHD11
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UniprotKB/SwissProt ID: Q8K4F5 (Q8K4F5)
Gene Name:
Abhd11
Organism: Mus musculus (Mouse)
Function: Catalyzes the hydrolysis of diacylglycerol in vitro and may function as a key regulator in lipid metabolism, namely by regulating the intracellular levels of diacylglycerol (By similarity). 1,2-diacyl-sn-glycerols are the preferred substrate over 1,3-diacyl-sn-glycerols. The enzyme hydrolyzes stearate in preference to palmitate from the sn-1 position of 1,2-diacyl-sn-glycerols (By similarity). Maintains the functional lipoylation of the 2-oxoglutarate dehydrogenase complex (OGDHc) through its interaction with the OGDHc by preventing the formation of lipoyl adducts (By similarity). In addition, is also required for the expansion and differentiation of embryonic stem cells (ESCs) (PubMed:32733886)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Mitochondrion matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8K4F5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
127 |
GLLPQLGLVP C VLVGHSMGGK |
CCCHHHCCCC C CCCCCCCCCC |
2.63% |
21278135
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