Protein Name:
WD repeat-containing protein 11
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UniprotKB/SwissProt ID: Q8K1X1 (Q8K1X1)
Gene Name:
Wdr11
Organism: Mus musculus (Mouse)
Function: Involved in the Hedgehog (Hh) signaling pathway, is essential for normal ciliogenesis (PubMed:29263200). Regulates the proteolytic processing of GLI3 and cooperates with the transcription factor EMX1 in the induction of downstream Hh pathway gene expression and gonadotropin-releasing hormone production (PubMed:29263200). WDR11 complex facilitates the tethering of Adaptor protein-1 complex (AP-1)-derived vesicles. WDR11 complex acts together with TBC1D23 to facilitate the golgin-mediated capture of vesicles generated using AP-1 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasmic vesicle. Golgi apparatus, trans-Golgi network
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8K1X1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
515 |
LLHKELSVHS C EVKGIEWTSL |
CCCEEEEEEE E EHHHHHHHHH |
4.15% |
20925432
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