Protein Name:
Fermitin family homolog 3
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UniprotKB/SwissProt ID: Q8K1B8 (Q8K1B8)
Gene Name:
Fermt3
Organism: Mus musculus (Mouse)
Function: Plays a central role in cell adhesion in hematopoietic cells (By similarity). Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3) (PubMed:18278053). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells (PubMed:19234461). Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs) (PubMed:18278053)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell projection, podosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8K1B8
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
235 |
LHSRWLDSSR C LMQQGIKAGD |
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| 2 |
435 |
PEGMSEIYLR C QDEQQYAQWM |
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