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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Multidrug and toxin extrusion protein 1

UniprotKB/SwissProt ID: Q8K0H1 (Q8K0H1)

Gene Name: Slc47a1

Organism: Mus musculus (Mouse)

Function: Multidrug efflux pump that functions as a H(+)/organic cation antiporter (PubMed:16641166, PubMed:19332510). Plays a physiological role in the excretion of cationic compounds including endogenous metabolites, drugs, toxins through the kidney and liver, into urine and bile respectively (By similarity). Mediates the efflux of endogenous compounds such as creatinine, vitamin B1/thiamine, agmatine and estrone-3-sulfate (By similarity). May also contribute to regulate the transport of cationic compounds in testis across the blood-testis-barrier (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Apical cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR045069 MATE_euk
IPR002528 MATE_fam

The S-nitrosylation sites of Q8K0H1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 466 FIARLNWKRA C QQAQVHANLK