Protein Name:
EARP and GARP complex-interacting protein 1
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UniprotKB/SwissProt ID: Q8K0G5 (Q8K0G5)
Gene Name:
Eipr1
Organism: Mus musculus (Mouse)
Function: Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network (By similarity). Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein (By similarity). Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex (By similarity). Controls proper insulin distribution and secretion, and retention of cargo in mature dense core vesicles (By similarity). Required for the stability of the endosome-associated retrograde protein (EARP) complex subunits and for proper localization and association of EARP with membranes (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus, trans-Golgi network
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8K0G5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
198 |
TAGRWSPHHN C TQVATASDTT |
CCCCCCEEEE E EEEEEECCCC |
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21278135
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