Protein Name:
Sodium/myo-inositol cotransporter 2
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UniprotKB/SwissProt ID: Q8K0E3 (Q8K0E3)
Gene Name:
Slc5a11
Organism: Mus musculus (Mouse)
Function: Involved in the sodium-dependent cotransport of myo-inositol (MI) with a Na(+):MI stoichiometry of 2:1. Exclusively responsible for apical MI transport and absorption in intestine. Can also transport D-chiro-inositol (DCI) but not L-fucose (By similarity). Exhibits stereospecific cotransport of both D-glucose and D-xylose (By similarity). May induce apoptosis through the TNF-alpha, PDCD1 pathway (By similarity). May play a role in the regulation of MI concentration in serum, involving reabsorption in at least the proximal tubule of the kidney (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane. Apical cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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