Protein Name:
Kin of IRRE-like protein 3
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UniprotKB/SwissProt ID: Q8IZU9 (Q8IZU9)
Gene Name:
KIRREL3
Organism: Homo sapiens (Human)
Function: Synaptic adhesion molecule required for the formation of target-specific synapses. Required for formation of target-specific synapses at hippocampal mossy fiber synapses. Required for formation of mossy fiber filopodia, the synaptic structures connecting dentate granule and GABA neurons. Probably acts as a homophilic adhesion molecule that promotes trans-cellular interactions and stabilize mossy fiber filipodia contact and subsequent synapse formation. Required for the coalescence of vomeronasal sensory neuron axons. May be involved in the hematopoietic supportive capacity of stroma cells; the secreted extracellular domain is directly responsible for supporting hematopoietic stem cells
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Secreted
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8IZU9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
398 |
VRQEDAGKYV C RAVVPRVGAG |
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