Protein Name:
Tumor protein p53-inducible nuclear protein 2
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UniprotKB/SwissProt ID: Q8IXH6 (Q8IXH6)
Gene Name:
TP53INP2
Organism: Homo sapiens (Human)
Function: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus. Nucleus, PML body. Cytoplasmic vesicle, autophagosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8IXH6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
214 |
KNQSSFIYQP C QRQFNY---- |
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