Protein Name:
GRIP and coiled-coil domain-containing protein 2
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UniprotKB/SwissProt ID: Q8IWJ2 (Q8IWJ2)
Gene Name:
GCC2
Organism: Homo sapiens (Human)
Function: Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Golgi apparatus, trans-Golgi network membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8IWJ2
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1061 |
TRQLRNSTLQ C ETINSDNEDL |
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| 2 |
257 |
IHQEEVKELM C QIEASAKEHE |
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| 3 |
399 |
ELLLAKEEQG C VIEKLKSELA |
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| 4 |
798 |
ESLAKINEEK C NLAFQRDEKV |
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| 5 |
889 |
LIQVEEVSQT C SKSEIHNEKE |
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| 6 |
92 |
LLEKAETEQQ C LSLKKENIKM |
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