Protein Name:
MAX gene-associated protein
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UniprotKB/SwissProt ID: Q8IWI9 (Q8IWI9)
Gene Name:
MGA
Organism: Homo sapiens (Human)
Function: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8IWI9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
2208 |
DEQLIKETKT C QENSDVFQQE |
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| 2 |
355 |
VPQLKQEISE C LIASSFEDDS |
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| 3 |
396 |
LDDYDYELGE C PEGVTVKQEE |
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