Protein Name:
WD repeat and FYVE domain-containing protein 1
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UniprotKB/SwissProt ID: Q8IWB7 (Q8IWB7)
Gene Name:
WDFY1
Organism: Homo sapiens (Human)
Function: Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines (PubMed:25736436)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Early endosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8IWB7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
287 |
EAPQWLESDS C QKCEQPFFWN |
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