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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Centrosomal protein of 97 kDa

UniprotKB/SwissProt ID: Q8IW35 (Q8IW35)

Gene Name: CEP97

Organism: Homo sapiens (Human)

Function: Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation (PubMed:17719545, PubMed:30375385). Required for recruitment of CCP110 to the centrosome (PubMed:17719545)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR050576 Cilia_flagella_integrity
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf

The S-nitrosylation sites of Q8IW35

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 676 PLFTQSQESS C DQNADWFIAS   
2 852 NAEVQGQQPE C DSTFQLLHVG