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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

UniprotKB/SwissProt ID: Q8IVS2 (Q8IVS2)

Gene Name: MCAT

Organism: Homo sapiens (Human)

Function: Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1) (PubMed:12882974, PubMed:19549604). This suggests the existence of the biosynthesis of fatty acids in mitochondria (PubMed:12882974). Also acts as a mitochondrial small ribosomal subunit (mt-SSU) assembly factor (PubMed:36482135)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001227 Ac_transferase_dom_sf
IPR014043 Acyl_transferase_dom
IPR016035 Acyl_Trfase/lysoPLipase
IPR016036 Malonyl_transacylase_ACP-bd
IPR052760 Mitochondrial_malonyltrans

The S-nitrosylation sites of Q8IVS2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 225 CKSLGIENPV C EVSNYLFPDC