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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ELKS/Rab6-interacting/CAST family member 1

UniprotKB/SwissProt ID: Q8IUD2 (Q8IUD2)

Gene Name: ERC1

Organism: Homo sapiens (Human)

Function: Regulatory subunit of the IKK complex. Probably recruits IkappaBalpha/NFKBIA to the complex. May be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. May be involved in vesicle trafficking at the CAZ. May be involved in Rab-6 regulated endosomes to Golgi transport

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Membrane. Golgi apparatus membrane. Presynaptic cell membrane. Cell projection, podosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019323 ELKS/CAST
IPR037245 FIP-RBD_C_sf
IPR019018 Rab-bd_FIP-RBD

The S-nitrosylation sites of Q8IUD2

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 258 QDSSSRTGEP C VAELTEENFQ