Protein Name:
Interferon regulatory factor 2-binding protein 1
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UniprotKB/SwissProt ID: Q8IU81 (Q8IU81)
Gene Name:
IRF2BP1
Organism: Homo sapiens (Human)
Function: Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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| InterPro ID |
Domain Name |
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IPR044882
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I2BP1/2_C3HC4-RING_sf |
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IPR022750
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Interferon_reg_fac2-bd1_2_Znf |
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The S-nitrosylation sites of Q8IU81
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
207 |
EKEKQQRNAD C LAELNEAMRG |
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| 2 |
239 |
VREQLLALSA C APFNVRFKKD |
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| 3 |
280 |
FELKLFTEYP C GSGNVYAGVL |
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| 4 |
363 |
QYPEPAPAAL C GPPPRAPSRN |
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