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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Dual specificity phosphatase Cdc25

UniprotKB/SwissProt ID: Q8GY31 (Q8GY31)

Gene Name: CDC25

Organism: Arabidopsis thaliana (Mouse-ear cress)

Function: Tyrosine protein phosphatase that dephosphorylates CDK complex and activate its kinase activity in vitro Arsenate reductase that plays a major role in the reduction of arsenate to arsenite and arsenic retention in roots (PubMed:16567632). Has an in vitro and in vivo arsenate reductase activity (PubMed:16507083, PubMed:16766666, PubMed:22562211). Plays no role in arsenic metabolism (PubMed:22879969, PubMed:25464340)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001763 Rhodanese-like_dom
IPR036873 Rhodanese-like_dom_sf

The S-nitrosylation sites of Q8GY31

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 134 NGWEASGKPV C RCAEVPCKGD