Protein Name:
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial
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UniprotKB/SwissProt ID: Q8CHT0 (Q8CHT0)
Gene Name:
Aldh4a1
Organism: Mus musculus (Mouse)
Function: Irreversible conversion of delta-1-pyrroline-5-carboxylate (P5C), derived either from proline or ornithine, to glutamate. This is a necessary step in the pathway interconnecting the urea and tricarboxylic acid cycles. The preferred substrate is glutamic gamma-semialdehyde, other substrates include succinic, glutaric and adipic semialdehydes (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion matrix
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8CHT0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
279 |
GDTVTSSEHL C GINFTGSVPT |
CCCCHHHHHH H HHHHHHCCCC |
5.77% |
21278135
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| 2 |
314 |
FRTFPRLAGE C GGKNFHFVHS |
CCCCHHHHHH H HHHHHHCCCC |
9.48% |
22178444
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| 3 |
94 |
FNHAHKVAKF C YADKALLNRA |
CCCCHHHHHH H HHHHHHCCCC |
2.42% |
22178444
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