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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Glycerol-3-phosphate phosphatase

UniprotKB/SwissProt ID: Q8CHP8 (Q8CHP8)

Gene Name: Pgp

Organism: Mus musculus (Mouse)

Function: Glycerol-3-phosphate phosphatase hydrolyzing glycerol-3-phosphate into glycerol. Thereby, regulates the cellular levels of glycerol-3-phosphate a metabolic intermediate of glucose, lipid and energy metabolism (PubMed:26755581). Was also shown to have a 2-phosphoglycolate phosphatase activity and a tyrosine-protein phosphatase activity. However, their physiological relevance is unclear (PubMed:24338473, PubMed:26755581). In vitro, also has a phosphatase activity toward ADP, ATP, GDP and GTP (PubMed:24338473)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR036412 HAD-like_sf
IPR006357 HAD-SF_hydro_IIA
IPR023214 HAD_sf
IPR006349 PGP_euk

The S-nitrosylation sites of Q8CHP8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 193 KAVRYLQQPD C LLVGTNMDNR  CCCCCCCCCH H HHHHHHHHHH  3.94% 21278135
2 217 ENGRFIAGTG C LVRAVEMAAQ  CCCCCCCCCH H HHHHHHHHHH  2.97% 21278135
3 243 IGKPSRFIFD C VSQEYGINPE  CCCCCCCCCH H HHHHHHHHHH  1.9%
4 272 LDTDILLGST C SLKTILTLTG  CCCCCCCCCH H HHHHHHHHHH  4.86%