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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein unc-45 homolog B

UniprotKB/SwissProt ID: Q8CGY6 (Q8CGY6)

Gene Name: Unc45b

Organism: Mus musculus (Mouse)

Function: Acts as a co-chaperone for HSP90 and is required for proper folding of the myosin motor domain. Plays a role in sarcomere formation during muscle cell development (PubMed:12356907, PubMed:18326487, PubMed:18478096). Is necessary for normal early lens development (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, myofibril, sarcomere, Z line. Cytoplasm, myofibril, sarcomere, A band. Cytoplasm, perinuclear region. Cytoplasm, cytosol

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_rpt
IPR024660 UCS_central_dom

The S-nitrosylation sites of Q8CGY6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 519 KLAKQCRKWL C NTAIDTRTRR  CHHHHHHHHH H HCCCCCCCCH  4.06% 21278135