Protein Name:
Aflatoxin B1 aldehyde reductase member 2
|
UniprotKB/SwissProt ID: Q8CG76 (Q8CG76)
Gene Name:
Akr7a2
Organism: Mus musculus (Mouse)
Function: Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). Has broad substrate specificity. Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Mitochondrion. Golgi apparatus. Cytoplasm
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
The S-nitrosylation sites of Q8CG76
|
| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
164 |
STPVEETLRA C HQLHQEGKFV |
CHHHHHHHHH H HHHHHHHHHC |
1.37% |
|
| 2 |
222 |
TRQVEAELLP C LRHFGLRFYA |
CHHHHHHHHH H HHHHHHHHHC |
5.42% |
21278135
|
|
