Protein Name:
BCAS3 microtubule associated cell migration factor
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UniprotKB/SwissProt ID: Q8CCN5 (Q8CCN5)
Gene Name:
Bcas3
Organism: Mus musculus (Mouse)
Function: Functions synergistically with PELP1 as a transcriptional coactivator of estrogen receptor-responsive genes. Stimulates histone acetyltransferase activity. Binds to chromatin (By similarity). Plays a role in angiogenesis. Participates in the regulation of cell polarity and directional endothelial cell migration by mediating both the activation and recruitment of CDC42 and the reorganization of the actin cytoskeleton at the cell leading edge. Promotes filipodia formation. Plays a regulatory role in autophagic activity. In complex with PHAF1, associates with the preautophagosomal structure during both non-selective and selective autophagy. Probably binds phosphatidylinositol 3-phosphate (PtdIns3P) which would mediate the recruitment preautophagosomal structures (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Preautophagosomal structure
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8CCN5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
479 |
QELTSKQGGR C SPVPGLSSSP |
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