Protein Name:
Vacuolar protein sorting-associated protein 53 homolog
|
UniprotKB/SwissProt ID: Q8CCB4 (Q8CCB4)
Gene Name:
Vps53
Organism: Mus musculus (Mouse)
Function: Acts as a component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Acts as a component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus, trans-Golgi network membrane. Endosome membrane. Recycling endosome
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
