Protein Name:
Dedicator of cytokinesis protein 2
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UniprotKB/SwissProt ID: Q8C3J5 (Q8C3J5)
Gene Name:
Dock2
Organism: Mus musculus (Mouse)
Function: Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endomembrane system. Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8C3J5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
607 |
RDVFSISTLV C STKLTQNVGL |
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