Protein Name:
Isoaspartyl peptidase/L-asparaginase
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UniprotKB/SwissProt ID: Q8C0M9 (Q8C0M9)
Gene Name:
Asrgl1
Organism: Mus musculus (Mouse)
Function: Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8C0M9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
114 |
LSAGAVSAVR C IANPVKLARL |
CCCCCCCCCC C CEEECCEEEE |
2.5% |
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| 2 |
132 |
ARLVMEKTPH C FLTGHGAEKF |
CCCCCCCCCC C CEEECCEEEE |
2.92% |
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| 3 |
179 |
KLEKGAQNAD C PKNSGTVGAV |
CCCCCCCCCC C CEEECCEEEE |
4.86% |
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| 4 |
219 |
KMVGRVGDSP C IGAGGYADNN |
CCCCCCCCCC C CEEECCEEEE |
5.33% |
21278135
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| 5 |
317 |
NGKLQAGIDL C ETRTRDLPC- |
CCCCCCCCCC C CEEECCEEEE |
4.44% |
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| 6 |
326 |
LCETRTRDLP C ---------- |
CCCCCCCCCC C CEEECCEEEE |
13% |
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