Protein Name:
Protein-cysteine N-palmitoyltransferase HHAT
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UniprotKB/SwissProt ID: Q8BMT9 (Q8BMT9)
Gene Name:
Hhat
Organism: Mus musculus (Mouse)
Function: Palmitoyl acyltransferase that catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling during limb development (PubMed:15075292). It also catalyzes N-terminal palmitoylation of DHH (By similarity). Promotes the transfer of palmitoyl-CoA from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane, where SHH palmitoylation occurs (By similarity). Plays a role in proper testis cord formation and the differentiation of Leydig cells (PubMed:24784881)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Golgi apparatus membrane
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Graphical Visualization of S-nitrosylation Sites:
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