Protein Name:
Neutral cholesterol ester hydrolase 1
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UniprotKB/SwissProt ID: Q8BLF1 (Q8BLF1)
Gene Name:
Nceh1
Organism: Mus musculus (Mouse)
Function: Hydrolyzes 2-acetyl monoalkylglycerol ether (1-O-alkyl-2-acetyl-sn-glycerol), the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor (PubMed:18164358, PubMed:20625037). May be responsible for the hydrolysis of cholesterol esters (such as cholesteryl (9Z-octadecenoate)) in macrophages (PubMed:18782767). Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds (PubMed:15840715, PubMed:16978018, PubMed:18164358)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Microsome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8BLF1
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
345 |
EALPKTYILT C EHDVLRDDGI |
CHHHHHHHHH H HHHHHHHHHC |
3.81% |
21278135
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