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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Trinucleotide repeat-containing gene 6B protein

UniprotKB/SwissProt ID: Q8BKI2 (Q8BKI2)

Gene Name: Tnrc6b

Organism: Mus musculus (Mouse)

Function: Plays a role in RNA-mediated gene silencing by both micro-RNAs (miRNAs) and short interfering RNAs (siRNAs). Required for miRNA-dependent translational repression and siRNA-dependent endonucleolytic cleavage of complementary mRNAs by argonaute family proteins. As scaffolding protein associates with argonaute proteins bound to partially complementary mRNAs and simultaneously can recruit CCR4-NOT and PAN deadenylase complexes

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, P-body

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR019486 Argonaute_hook_dom
IPR052068 GW182_domain
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR032226 TNRC6_PABC-bd
IPR034925 TNRC6B_RRM