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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Isoleucine--tRNA ligase, mitochondrial
UniprotKB/SwissProt ID: Q8BIJ6 (Q8BIJ6)

Gene Name: Iars2

Organism: Mus musculus (Mouse)

Function: Aminoacyl-tRNA synthetase that catalyzes the specific attachment of isoleucine to its cognate tRNA (tRNA(Ile))

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001412 aa-tRNA-synth_I_CS
IPR002300 aa-tRNA-synth_Ia
IPR033708 Anticodon_Ile_BEm
IPR002301 Ile-tRNA-ligase
IPR023585 Ile-tRNA-ligase_type1
IPR050081 Ile-tRNA_ligase
IPR013155 M/V/L/I-tRNA-synth_anticd-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR009008 Val/Leu/Ile-tRNA-synth_edit
IPR010663 Znf_FPG/IleRS
The S-nitrosylation sites of Q8BIJ6
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 1002 KHTSETADAL C PRCAEVIGAK  CCCCCCCCCC C HHHHHHCCCC  1.83% 21278135
2 1005 SETADALCPR C AEVIGAK---  CCCCCCCCCC C HHHHHHCCCC  1.98% 21278135
3 110 QRERKVKTEF C LHDGPPYANG  CCCCCCCCCC C HHHHHHCCCC  2.41% 21278135
4 311 PWTIPANQAI C YMPEAKYAVV  CCCCCCCCCC C HHHHHHCCCC  2.39% 21278135
5 364 FSGVDLEGGT C SHPLTPDKVS  CCCCCCCCCC C HHHHHHCCCC  3.88% 21278135
6 465 KEENIVHSYP C DWRTKTPVLI  CCCCCCCCCC C HHHHHHCCCC  6.27% 21278135
7 819 ENEKDPKRRS C QTALAEILDV  CCCCCCCCCC C HHHHHHCCCC  3.85% 21278135
8 883 PGLEEAVESA C AMRDSFLGSI  CCCCCCCCCC C HHHHHHCCCC  4.21% 21278135
9 91 SDMELEIQQK C GFSELYSWQR  CCCCCCCCCC C HHHHHHCCCC  6.06% 21278135