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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Armadillo repeat-containing X-linked protein 3

UniprotKB/SwissProt ID: Q8BHS6 (Q8BHS6)

Gene Name: Armcx3

Organism: Mus musculus (Mouse)

Function: Regulates mitochondrial aggregation and transport in axons in living neurons (PubMed:22569362, PubMed:23844091). May link mitochondria to the Trak2-kinesin motor complex via its interaction with Miro and Trak2 (PubMed:22569362). Mitochondrial distribution and dynamics is regulated through Armcx3 protein degradation, which is promoted by PCK and negatively regulated by Wnt1 (PubMed:23844091). Enhances the Sox10-mediated transactivation of the neuronal acetylcholine receptor subunit alpha-3 and beta-4 subunit gene promoters (PubMed:19304657)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Mitochondrion outer membrane. Cytoplasm. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011989 ARM-like
IPR006911 ARM-rpt_dom
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR051303 Armcx_regulator