Protein Name:
EH domain-containing protein 2
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UniprotKB/SwissProt ID: Q8BH64 (Q8BH64)
Gene Name:
Ehd2
Organism: Mus musculus (Mouse)
Function: ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis (PubMed:24508342). Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4 (PubMed:14676205). Required for fusion of myoblasts to skeletal muscle myotubes. Required for normal translocation of FER1L5 to the plasma membrane (PubMed:18502764, PubMed:21177873). Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by constraining caveolae at the cell membrane (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Membrane, caveola. Endosome membrane. Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q8BH64
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
138 |
FGNTFLNRFM C AQLPNQVLES |
CCCCCCCCCC C CCCHHHHHHH |
1.69% |
21278135
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| 2 |
356 |
HHISPGDFPD C QKMQELLMAH |
CCCCCCCCCC C CCCHHHHHHH |
4.22% |
21278135
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