Protein Name:
Interleukin-17 receptor E
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UniprotKB/SwissProt ID: Q8BH06 (Q8BH06)
Gene Name:
Il17re
Organism: Mus musculus (Mouse)
Function: Specific functional receptor for IL17C, signaling through the NF-kappa-B and MAPK pathways. Requires TRAF3IP2 /ACT1 for signaling. Crucial regulator in innate immunity to bacterial pathogens, such as Citrobacter rodentium. Isoform 4 and isoform 5 may be either cytoplasmic inactive or dominant active forms. Isoform 2 and isoform 3 may act as soluble decoy receptors
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Secreted. Secreted. Cytoplasm. Cytoplasm
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Graphical Visualization of S-nitrosylation Sites:
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