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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Prostaglandin reductase-3
UniprotKB/SwissProt ID: Q8BGC4 (Q8BGC4)

Gene Name: Ptgr3

Organism: Mus musculus (Mouse)

Function: Functions as 15-oxo-prostaglandin 13-reductase and acts on 15-keto-PGE1, 15-keto-PGE2, 15-keto-PGE1-alpha and 15-keto-PGE2-alpha with highest efficiency towards 15-keto-PGE2-alpha. Overexpression represses transcriptional activity of PPARG and inhibits adipocyte differentiation

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Peroxisome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR013149 ADH-like_C
IPR013154 ADH-like_N
IPR011032 GroES-like_sf
IPR036291 NAD(P)-bd_dom_sf
IPR020843 PKS_ER
IPR002364 Quin_OxRdtase/zeta-crystal_CS
IPR051397 Zn-ADH-like_protein
The S-nitrosylation sites of Q8BGC4
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 218 EKAAFLKSIG C DRPINYRTEP  CHHHHHHCCC E EEECHHHHHH  21278135
2 55 FHEAVTLRRD C PVPLPGDGDL  CHHHHHHCCC E EEECHHHHHH  21278135